WO1998010083A1 - Herpesvirus saimiri as viral vector - Google Patents: The invention relates to a means to a herpesvirus saimiri that has been genetically modified by mutating and/or deleting specific essential and non-essential genes. The essential genes are required in replication of viral genes and are needed for viral proliferation. The non-essential genes can represent sites for the insertion of heterologous genetic material, namely therapeutic genes.
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